Abstract

This study reports an eco-friendly, cost effective and biological synthesis of meropenem antibiotic conjugated silver nanoparticles (mer-AgNPs). The synthesized (mer-AgNPs) nanoparticles were characterized using UV–Visible spectrophotometer, transmission electron Microscope, Fourier-transform infrared spectroscopy (FT-IR), TEM. mer-AgNPs have increased antibacterial activity against both Gram-positive and Gram–negative bacteria (Staphylococcus aureus (MTCC 96), Listeria monocytogens (MTCC 657), Vibrio vulnificus (MTCC 1145), Shigella flexneri (MTCC 1457), Escherichia coli (MTCC 1687), and Salmonlla typhimurium (MTCC 3224). In addition, mer-AgNPs are highly effective against biofilm producers compared to the antibiotic alone. The photocatalytic activity shows good results in Congo red with AgNPs.

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