Abstract
The stems of red dragon fruit (Hylocereus polyrhizus) are known to have several antibacterial compounds. The purpose of this study was to determine the antibacterial activity of ethanol extract, n-hexane, ethyl acetate, and water fractions from dragon fruit stems on the growth of Methicillin-resistant Staphylococcus aureus (MRSA), and to determine the types of compounds that are antibacterial. The data on the greatest antibacterial activity was found at a concentration of 30% both in the ethanol extract (1,850cm); n-hexane fraction (1,948 cm); ethyl acetate fraction (1,640 cm) and water fraction (0.884 cm). Meanwhile, the results of contact bioautography showed that the antibacterial compounds of Methicillin-resistant Staphylococcus aureus (MRSA) were flavonoids, saponins, and steroids.
Highlights
Staphylococcus aureus is a major pathogen in humans and almost everyone has experiencedS. aureus infections that vary in severity, from food poisoning to mild to severe skin infections that are life-threatening
Methicillin Resistant Staphylococcus aureus (MRSA) is a strain of Staphylococcus aureus that is resistant to various antibiotics
The purpose of this study was to determine the antibacterial activity of ethanolic extract, nhexane, ethyl acetate, and water fractions from dragon fruit stems against the growth of Methicillin-resistant Staphylococcus aureus (MRSA), and to determine the type of compound with antibacterial properties
Summary
Staphylococcus aureus is a major pathogen in humans and almost everyone has experienced. S. aureus infections that vary in severity, from food poisoning to mild to severe skin infections that are life-threatening. If S. aureus spreads and bacteremia develops, endocarditis, acute hematogenous osteomyelitis, meningitis, and lung infections may occur (Triana et al, 2014). Methicillin Resistant Staphylococcus aureus (MRSA) is a strain of Staphylococcus aureus that is resistant to various antibiotics. In recent years the incidence of resistance to vancomycin antibiotics has begun to emerge. This resistance can be caused by irrational use of antibiotics and the insertion of a Deoxyribonucleic Acid (DNA) element called Staphylococcal Casette Chromosome mec SCC (Ajrina et al, 2015)
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