Anti‑bacterial activity of the methanolic extract of leucas hyssopifolia (Benth.)

Abstract

Context: Methanolic extract of Leucas hyssopifolia roots was investigated for its anti‑bacterial property. Aim: Evaluation of anti‑bacterial activity of Leucas hyssopifolia Benth. Settings and Design: Roots of the plant were collected, extracted and finally evaluated for their anti‑bacterial activity. Materials and Methods: Paper disc diffusion method and microdilution technique were employed for the determination of zone of inhibition and minimal inhibitory concentration, respectively. Results: The extract showed anti‑bacterial activity against all the tested bacterial strains except Escherichia coli. Conclusions: Anti‑bacterial activity of extract of Leucas hyssopifolia roots may be due to the presence of secondary plant metabolites like terpenoids, steroids and flavonoids, which are present in the extract. The extract can be further studied for the isolation of chemical compounds and their biological activity. Key words: Anti‑bacterial activity, Leucas hyssopifolia, minimal inhibitory concentration, phytochemical screening