Antibacterial activity of tannins from the leaves of Solanum trilobatum Linn

A Doss

doi:10.17485/ijst/2009/v2i2.5

Abstract

Compounds of pharmacological interest (tannins) were isolated from the plant species, Solanum trilobatum Linn and assayed against the bacteria, Staphylococcus aureus, Streptococcus pyrogens, Salmonella typhi, Pseudomonas aeruginosa, Proteus vulgaris and Escherichia coli using agar diffusion method. Tannins exhibited antibacterial activities against all the tested microorganisms. S.aureus was the most resistant to tannins isolated from the plant material followed by Streptococcus pyrogens, Salmonella typhi, Escherichia coli, Proteus vulgari and Pseudomonas aeruginosa. Minimum inhibitory concentration of the tannins ranged between 1.0 and 2.0 mg/ml while the minimum bactericidal concentration ranged between 1.5 and 2.0 mg/ml. Keywords: Solanum trilobatum, tannins, methanol, bacterial pathogens, minimum inhibitory concentration, minimum bactericidal concentratio

Highlights

Tannins are polyphenols that are obtained from various parts of different plants (Gajendiran & Mahadevan, 1990)
In addition to use in leather processing industries, tannins have shown potential antiviral (Lin et al, 2004), antibacterial (Akiyama et al, 2001; Funatogawa et al, 2004), and antiparasitic effects (Bhagavathi et al, 1999; Yang et al, 2000; Tanimura et al, 2005)
This study was carried out to evaluate the antibacterial properties of tannins isolated from S.trilobatum

Summary

Results and discussion toxic activity against bacteria and may assume

The presence of antibacterial substances in the pharmacological importance. higher plants is well established (Srinivasan et al., 2001). The presence of antibacterial substances in the pharmacological importance. Higher plants is well established (Srinivasan et al., 2001). Plants have provided a source of inspiration for. Novel drug compounds as plants derived medicines have made significant contribution towards human health. Solanum trilobatum was tested and compared to that of antibacterial antibiotic Streptomycin. 0.35 pointed out that these tannins possessed the highest antibacterial activity against the bacteria, Staphylococcus aureus and. Proteus vulgaris at 2.5mg/ml Strepto concentration (Table.1), whereas they -mycin were moderately active against the NA – No Activity remaining bacteria. Several plants which are rich in tannins have been shown to possess antimicrobial activities against a number of microorganisms. (2007) investigated the antibacterial activity of leaf extract Dichrostachys cinerea and reported that tannins, alkaloids and glycosides were detected

Proteus vulgaris

Findings

Escherichia coli