Abstract
A series of quinolines containing a cyclic hydroxamic acid group have been prepared and tested for antibacterial activity. Results show that the activity exhibited by 3-alkylquinoline hydroxamic acids is influenced by both the nature of the other substituents in the molecule and by the size of the alkyl group. One cyclic hydroxamic acid, 1,2-dihydro-1,4-dihydroxy-3-ethyl-2-oxoquinoline, showed some hypnotic activity.
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