Abstract
Staphylococcus aureus, which is commonly found in hospitals, has become a major problem in infection control. In this study, Ag/80S bioactive ceramics used for enhanced antibacterial applications have been developed. An in vitro bioactivity test of the Ag/80S bioactive ceramic powders was performed in a phosphate-buffered saline (PBS). To explore the antibacterial activity of the Ag/80S bioactive ceramic powders, the Kirby-Bauer susceptibility test, the kinetics of microbial growth analysis and the colony-forming capacity assay were used to determine their minimum inhibitory concentration (MIC) against methicillin-resistant Staphylococcus aureus (MRSA). The results confirmed that the Ag/80S bioactive ceramic powders have antibacterial activity against MRSA (ATCC 33592) and MRSA (ATCC 49476).
Highlights
The World Health Organization has pointed out that the international public health issues of the new century are infectious diseases, and they will become one of the most serious diseases that threaten human health [1]
The Ag/80S bioactive ceramic powders were prepared using a co-template process of the sol-gel technique [24]
The surface area decreases as the proportion of added Ag increases
Summary
The World Health Organization has pointed out that the international public health issues of the new century are infectious diseases, and they will become one of the most serious diseases that threaten human health [1]. With the changes in human lifestyles, viruses or pathogenic microorganisms continue to adapt and mutate, leading to the emergence of various infectious diseases. Staphylococcus aureus is a gram-positive bacterium that is naturally found on humans. For reasons that are not currently known, it becomes a major problem in infection control. Because of the convenience of hospitalization and the country’s dense population, patients with Staphylococcus aureus infection are chronically ill or have been recently treated for different reasons [2]. In order to alleviate this problem, clinicians, scholars and experts have conducted research on the molecular resistance mechanisms of Staphylococcus aureus, which in recent years has become moderately resistant against vancomycin [3,4,5]
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