Abstract
Background: Antimicrobial resistance is a major problem in treatment and public health, and it has been increasing over the last few decades. Hence, serious measurements are needed to overcome this challenge. In this study, we evaluated antibacterial and antifungal activity of some nanocomposites including titanium dioxide (5a), polyimide nanocomposites containing cerium oxide (5b), silver-titanium dioxide nanoparticles prepared under desired conditions (5c), polyaniline/wheat husk ash PANI /WHA (5d), Ag-TiO2 prepared by sol–gel route (5e), and cellulose-graphene (5f) against some bacterial and fungal strains, which are the most common agents in many infectious diseases. Methods: The nanoparticles were prepared in desired condition. The agar dilution and well agar diffusion methods were used for determination of inhibition zoon and minimum inhibitory concentration (MIC) during preliminary evaluation of antimicrobial activity against Staphylococcus aureus, Streptococcus pyogenes, Pseudomonas aeruginosa, Escherichia coli and Candida albicans. Results: The results showed that the nanocomposites had good activity against gram-negative bacteria. Conclusions: Our results showed that the inhibitory activity of these nanocomposites on gram-negative bacteria was better than gram-positive bacteria.
Highlights
Antimicrobial resistance is a major problem in treatment and public health, and it has been increasing over the last few decades
Measurement of Antimicrobial Activity The antimicrobial natures of nanocomposites including TiO2 (5a), polyimide nanocomposites containing cerium oxide (5b), silver-titanium dioxide nanoparticles prepared under desired conditions (5c), polyaniline/wheat husk ash PANI /WHA (5d), Ag-TiO2 prepared by sol–gel route (5e), and cellulose-graphene (5f) were measured according to their zone of inhibition against desired microorganisms
In this study, the antimicrobial activity of some nanocomposites including TiO2 (5a), polyimide nanocomposites containing cerium oxide (5b), silvertitanium dioxide NPs prepared under desired conditions (5c), polyaniline/wheat husk ash PANI /WHA (5d), AgTiO2 prepared by sol–gel route (5e), and cellulose-graphene (5f) were evaluated against important human pathogens
Summary
Antimicrobial resistance is a major problem in treatment and public health, and it has been increasing over the last few decades. The high level of resistance in different microorganisms to a majority of antimicrobial agents is one of the global threats, and researchers have always been struggling to cope with infectious diseases causing mortality and morbidity worldwide To overcome this threat, the synthesis and discovery of new compounds to replace existing antimicrobial agents is an effective strategy. The size of NPs provides high interactions in small molecule antibiotics [1,2] and high surface of adhesion in ligands; the use of NPs can be a good strategy to enhance interactions in target bacteria [3] Recent research on such NPs as TiO2, cellulose-graphene, and polyaniline indicated encouraging results for antibacterial nature [4]. We synthesized some NPs including TiO2 [13], polyimide nanocomposites containing cerium oxide [14], silver-titanium dioxide nanoparticles (AgTiO2) prepared under desired conditions [15] and sol–
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
