Abstract

Mechanical alloying and annealing at 1150 °C for 2 h under an argon atmosphere were used to prepare Ti–45S5 bioglass nanocomposites. Ti–45S5 bioglass material was chemically modified by silver. The antibacterial activity of Ti–10% 45S5 bioglass nanocomposite containing silver against Streptococcus mutans and Staphylococcus aureus was studied. Nanocomposites were characterized by X-ray diffraction, scanning electron microscopy equipped with an electron energy dispersive spectrometer and transmission electron microscopy to evaluate phase composition, crystal structure and grain size. In vitro bacterial adhesion study indicated a significantly reduced number of Streptococcus mutans and Staphylococcus aureus on the bulk nanostructured Ti–45S5 bioglass–Ag plate surface in comparison to that on microcrystalline Ti plate surface. Nanostructured Ti-based biomaterials can be considered to be the future generation of dental implants.

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