Abstract
Streptococcus mutans (S. mutans) and Staphylococcus aureus (S. aureus) pathogenicity that alter biofim, has become one of risk factor in orthodontic treatment. The medicinal plant’s Butterfly pea efficacy as an antibacterial agent should be confirmed in dentistry. The purpose of this study is to investigate the antibacterial activity of Medan butterfly pea corolla extract (BPCE) against S. mutans ATCC®25175™ and S. aureus ATCC®6538™. This is a laboratory experiment with Post Test Only Group Design. The minimum inhibitory concentration of BPCE is 6.25 mg/mL. The best concentration of butterfly pea extract to inhibit biofilm formation (antibiofilm) is 100 mg/mL. There was a significant difference (p < 0.05) for antibiofilm activity assays and determination of intramembrane cellular leakage. Although Medan BPCE was inadequate enough in forming antibiofilm and caused intramembrane leakage of S. mutans and S. aureus, further studies in exploring the potential morphological traits of these herbs related to orthodontic products are quite promising.
Highlights
Colonies of Streptococcus mutans (S. mutans) as oral bacteria on the tooth surface could decrease the pH of the oral cavity to a critical level which will cause demineralization of enamel and leads to caries
The salivary pellicle is a mediator in which oral bacteria can attach to tooth surfaces and dental restorations
This pellicle acts as the receptor for several bacteria in the oral cavity, which is the iatrogenic effect of malocclusion or fixed orthodontic treatment
Summary
Colonies of Streptococcus mutans (S. mutans) as oral bacteria on the tooth surface could decrease the pH of the oral cavity to a critical level which will cause demineralization of enamel and leads to caries. The role of Staphylococcus aureus (S. aureus) has been considered in the differential diagnosis of oral cavity disease and cross-infection sources in a large dataset of retrospective laboratory data (McCormack et al 2015). The salivary pellicle is a mediator in which oral bacteria can attach to tooth surfaces and dental restorations. This pellicle acts as the receptor for several bacteria in the oral cavity, which is the iatrogenic effect of malocclusion or fixed orthodontic treatment. Previous studies stated that the saliva pellicle plays a significant role in initiating oral
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