Abstract

ObjectiveTo evaluate the in vitro activities, of three honeys sample, and Nigella sativa (N. sativa) against Pseudomonas aeruginosa (P. aeruginosa) alone and in combination. MethodsThe antibacterial test and minimum inhibition concentration (MIC) was determined by using agar well diffusion and dilution methods respectively against P. aeruginosa. ResultsThe MIC for the three varieties of honey without N. sativa against P. aeruginosa ranged between 46% and 50% (v/v). Addition of N. sativa (8%) resulted in synergistic bactericidal activity. An MIC drop was noticed with each variety and it ranged between 77.77% and 84.21%. ConclusionsThese antibacterial properties would warrant further studies on the clinical applications of N. sativa and honey against P. aeruginosa.

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