Abstract

Objective: The aims of this present study were to formulate antiacne cream consisting ethanolic extract of bawang dayak and evaluate antibacterialactivity of cream on day 0 and day 7 to see stability activity and preparation.Methods: Cream formula of bawang dayak was evaluated organoleptic characteristics, homogeneity, pH, adhesion test, dispersion test, and in vitroantibacterial against Propionibacterium acnes.Results: The results of evaluate cream homogeneity were F3 and F4 on day 7 separate and non-homogen but all formula pH suitable for topicalapplication. On day 0, F1 and F2 shown antibacterial activity in category weak activity, F3 and F4 in category moderate activity, while on day 7 allformula have antibacterial activity in category weak activity.Conclusion: All cream formula potentials inhibit against P. acnes but this research must be improved both of preparation and stability activity.

Highlights

  • Acne vulgaris is one of the problems experienced by teenagers and adults because in this modern era, physical appearance is one of the most important things that must be considered

  • Evaluation test of cream formula Organoleptic appearance The results of organoleptic test on day 0 showed that F1 had a lighter brown color than other formulas, it caused the concentration of ethanolic extract bawang dayak less concentration than other formulas

  • Homogeneity observation The observation of cream bawang dayak showed on day 0 all formulation homogen, but day 7, F3 and F4 showed separation phase between the oil phase and the water phase (Table 3)

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Summary

Introduction

Acne vulgaris is one of the problems experienced by teenagers and adults because in this modern era, physical appearance is one of the most important things that must be considered. Acne is not a serious disease, but it can lead depression and loss of confidence. There are many causes of acne such as hormone level, fat or oil in skin, and a bacterium like Propionibacterium acnes [1]. Many cosmetic products that offer to improve acne problems, nature provides a solution to these [2]. Bawang dayak is one of traditional medicines in Central Kalimantan. Extract ethanol of bawang dayak can inhibit P. acnes, so in this research, ethanol extract was made in cream formulation to improve the efficiency of using traditional medicine

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