Abstract

The emergence of new diseases and development of drug resistance has increased in recent years. The prime focus is in need for novel and safe bioactive compounds to support all aspects of mankind. Ever increasing diseases throttled search for bioactive compounds and drug development for the public health. The present study was conducted to evaluate the effects of culture filtrate of isolated endophytes; Melanospora fusispora, Alternaria alternata, Fusarium moniliforme and Cladosporium Cladosporium from Ocimum sanctum which were able to inhibit the growth of Salmonella typhii and Salmonella typhimurium. It is concluded that endophytes isolated from Ocimum sanctum leaf possess certain compounds with therapeutic value against Salmonella typhii and Salmonella typhimurium.

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