Abstract
Antibacterial Activity of Coastal Plants and Marine Sponges from Kei Island Indonesia against Bacterial Fish Pathogens
Highlights
The purified substance was tested for minimum inhibitory concentration (MIC) against seven bacterial fish pathogens namely Streptococcus sp., Vibrio parahaemolyticus, V. alginolyticus, V. harveyi, Photobacterium damselae, Aeromonas hydrophila and A. dhakensis
The fraction obtained from the column chromatography showing the highest antibacterial activity was determined for its minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC)
This paper describes the antibacterial activity of several coastal plants and marine sponges
Summary
Coastal plants and sponges are marine resources that have been widely known as producers of bioactive compounds.[1,2,3] They are rich sources of alkaloids, saponins, tannins, flavonoids, terpenoids, and glycosides[1,4] many of which exhibit various bioactivities including anticancer,[5] antifungal,[2,3,6] antiviral,[4] antioxidant[7,8,9] and antibacterial activities.[2,4,6,8,10,11] The application of antibacterial compounds from coastal plants and sponges are limited in medication of disease caused by human pathogenic bacteria[12,13] and have been applied to overcome the problem of fish bacterial infections.[2,12]. To the best of our knowledge, research on the antibacterial substances from coastal plants and sponges from Kei Islands has never been conducted. When we screened coastal plants and sponges from this island for anti-tuberculosis activity, we found several extracts active against fish pathogenic bacteria. The purposes of this study were to extract secondary metabolites from the coastal plants and sponges, to evaluate antibacterial activity, and to partially purify the potential substances
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