Abstract
New 2-amino-4-aryl-3-cyanopyridines were obtained by the three-component condensation of arylidenemalononitriles, malononitrile and (di)amine system or acetoacetanilide. Antibacterial activity of all synthesized compounds against the Gram-negative bacteria E. coli and the Gram-positive B. subtilis was tested, the only representative showed a substantial antimicrobial effect.
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