Abstract
To enhance the osteointegration and antibacterial property of titanium (Ti) implant, zinc calcium phosphate chemical conversion (Zn-Ca-PCC) was fabricated on pure Ti by phosphate chemical conversion technique. The surface of the coating was verified by combined techniques of scanning electron microscopy, energy-dispersive X-ray spectrometry, atomic force microscopy and water contact angle measurements. Plate-like Zn-Ca-PCC coatings are built up on the surface of Ti. The results obtained from the antibacterial studies suggest that the Zn-Ca-PCC coatings can greatly inhibit the growth of both Gram-positive (Staphylococcus aureus) and Gram-negative (Pseudomonas aeruginosa) bacteria. Moreover, the in vitro evaluations demonstrate that the adhesion, proliferation and differentiation of osteoblasts on Zn-Ca-PCC coatings were significantly enhanced compared with pure Ti. In conclusion, innovative Zn-Ca-PCC coatings on Ti with excellent antibacterial activity and biocompatibility are promising candidates for orthopedic and dental implants.
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