Abstract
One of the natural ingredients that can be used as medicinal plants is kundur fruit (Benincasa hispida Thunb. Cogn). Kundur is one of the plants that contain compounds that are efficacious in medicine. The people of the Moronene tribe in Southeast Sulawesi used to consume kundur fruit in a shredded way to treat typhoid caused by bacterium Salmonella typhi (S. Typhi). The general objective of this study was to determine the bioactivity of the ethanol extract of kundur fruit (B. hispida) as an antibacterial S. typhi. Determination of antibacterial activity was carried out using the broth microdilution method. The results showed that the ethanol extract of kundur fruit had inhibitory activity on the growth of S. typhi bacteria with a minimum inhibitory concentration (MIC) of 800 μg / mL. This activity was compared with chloramphenicol with a MIC value of 8 μg / mL. In conclusion, the ethanol extract of kundur fruit has the potential as a source of antibacterial compounds against S. typhi.
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