Abstract
AbstractThe titled compound 1,4-diazacycloheptane have vibrational freedom which allows it to coordinate to metal through 1st and 4th positions. Copper (II) and Nickel (II) complexes of DACH were prepared and characterized through UV-Visible, FT-IR, elemental analyses, conductance, and magnetic susceptibilities and compared to the results published in Inorg. Chem., 8(3), 528 (1969). The prepared complexes bearing different coordinating or non-coordinating anions were screened against four different pathogenic bacterial strains to study anionic effect on antibacterial activity. The MIC values of all the compounds suggest that [Cu(DACH)2Br2] is almost inactive against the tested microbes except Staph aureus. Rest of the metal complexes are active at their respective MIC values.
Highlights
Acyclic molecules containing the linkage -N(CH2)N- have been exploited as multidentate ligands for transition metal ions where it coordinates as multidentate ligand
The metal complexation of ligands containing oxygen, nitrogen or sulfur have been coordinated with metals like copper, zinc, cobalt and iron, showing enhanced antihypertensive, antimalarial, antimicrobial properties
The complexes of the transition metal ions have been found as efficient electron transfer agents in many biological processes [14,15,16,17,18]
Summary
Acyclic molecules containing the linkage -N(CH2)N- have been exploited as multidentate ligands for transition metal ions where it coordinates as multidentate ligand. The complexes of the transition metal ions have been found as efficient electron transfer agents in many biological processes [14,15,16,17,18]. They are acting as promoters for oxygen transport reaction [19,20,21,22,23]. Antibacterial Activities of Transition Metal complexes of Mesocyclic Amidine 1,4-diazacycloheptane (DACH) 937
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
