Abstract
Potentillareptans is widely used in traditional medicine as an astringent, for treating diarrhoea, haemorrhoids and for bleeding gums. A recent ethnobotanical study has reported on the anti-mastitis effects of the aerial parts of P.reptans decoction. The aim of the present study is to evaluate the antibacterial potential of extracts and fractions, obtained from aerial parts of P.reptans against three strains of Staphylococcusaureus. The observed MICs were within the range of 0.325 – 2.5 mg/ml. Studied extracts and their fractions exerted mostly bacteriostatic effect, with the n-hexane fraction of hydroethanolic extract being the most active (MIC 0.313 mg/ml against S.aureus ATCC 6538 P). However, further investigations are necessary to reveal the precise mode of action of P.reptans against mastitis.
Highlights
Potentilla reptans L. is a stoloniferous perennial plant, belonging to the Rosaceae family, which is distributed in the Northern Hemisphere (Markova 1973)
The present study aims to evaluate the antibacterial potential of extracts and fractions, obtained from aerial parts of Potentilla reptans against three strains of Staphylococcus aureus, including the methicillin-resistant strain, in order to verify the ethnobotanical use of the plant against mastitis
Antimicrobial susceptibility testing was performed with the following bacterial strains: Staphylococcus aureus ATCC 6538 P (American Type Cell Culture, USA), S. aureus FDA 209(ATCC 6538, American Type Cell Culture, USA), methicillin-resistant S. aureus (MRSA) 1337 (Collection of the Stephan Angeloff, Institute of Microbiology, Bulgaria)
Summary
Potentilla reptans L. is a stoloniferous perennial plant, belonging to the Rosaceae family, which is distributed in the Northern Hemisphere (Markova 1973). A study has documented a new ethnobotanical report for the anti-mastitis effect of P. reptans in the form of aerial parts decoction (Kozuharova et al 2012). Mainly phenolics, have so far been isolated from the aerial parts from P. reptans. Mincheva AM et al.: Antibacterial acticivity of extracts from Potentilla reptans L
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