Abstract
The effect of N (2-hydroxyethyl) palmitamide, ethanolamine hydrochloride, and a variety of fatty acids on passive anaphylaxis, serotonin, and histamine toxicity in the mouse was studied. The above compounds were found to be active in suppressing anaphylaxis and serotonin toxicity at low concentrations (about 5 mg. per kilogram), but they were shown to have no effect on histamine toxicity. Data presented indicate that fatty acids can act as potent pharmacologic agents.
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