Abstract
This chapter focuses on antiallergic and antitussive drugs. Hypersensitivity reactions to cromolyn sodium are uncommon, but well documented. They may occur after many months of use of antiallergic drugs. A striking negative finding with respect to adverse effects related to the absence in man of serious effects upon the kidney circulation, despite the fact that such effects had been detected around 1970 when the drug was investigated toxicologically in monkeys; such instances point to the risks of allowing animal toxicity studies to determine the fate of a new drug. On the other hand, Ketotifen is an orally active antihistamine with antiallergic properties. Side effects are rarely a problem. The chapter discusses cough remedies one of the example being mofoxine (arphosal) that is an antitussive substance possibly having antiphlogistic and sedative properties.
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