Abstract
Cancer may be a major public ill health, with significant associated death and disability. It is the second leading explanation for death in developed countries and is one among the three leading causes of death for adults in developing countries. Cancer which causes the morbidity and mortality in worldwide, approximately 14 million new cases in 2012.The number of latest cases is predicted to rise by about 70% over the next 2 decades. The present work was aimed to investigate the effect of curcumin/chitosan-coated iron oxide nanoparticles for topical application on L132 cells, for example, cytotoxicity, Reactive oxygen species (ROS) and induction of apoptosis. Diseases resulting from dermal exposure may have a big impact on human health. Cytotoxic potential of curcumin/chitosan-coated iron oxide nanoparticles was measured by tetrazolium bromide (MTT assay) in L132 cells. ROS assay and cell cycle were used to confirm the basis of apoptosis. Apoptosis was investigated by Annexin V with the Propidium iodide method in Flow cytometryanalysis.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
