Abstract
Salama M El Darier, Sania A Kamal, Ream I Marzouk and Iman H Nour* Author Affiliations Health Center Romareda Seminar, Spain Received: April 14, 2021 | Published: April 21, 2021 Corresponding author: Botany and Microbiology Department, Faculty of Science, Alexandria University, Egypt DOI: 10.26717/BJSTR.2021.35.005674
Highlights
Cancer is a rapid division of abnormal cells which grow beyond their normal limits
This study aimed to assess the anti-proliferative activities of L. fragilis and L. nudicaulis ethanol extracts through the Sulforhodamine B (SRB) assay, in vitro, on six cell lines; hepatocellular carcinoma (Hep Hepatocellular Carcinoma Cell Line (G2)), prostatic carcinoma (PC-3), colorectal carcinoma (HCT116), non-small cell lung carcinoma (H1299), breast adenocarcinoma (MCF7) and colon adenocarcinoma (Caco-2)
IC50 values were estimated by a linear least-squares regression of the growth values versus the logarithm of the extract concentration; only concentrations that yielded growth values between 10% and 90% were used in the calculation
Summary
Cancer is a rapid division of abnormal cells which grow beyond their normal limits. It can attack adjacent parts of the body and spread to other organs. (Asteraceae, Cichorioideae, Cichorieae) is polymorphic and controversial genus with confused intraspecific delimitation. It comprised about 54 species and 10 subspecies distributed in different geographical regions [7]. Despite the richness of Launaea species with different phenolic compounds such as flavonoids, coumarins and terpenoids [11,12,13,14], only limited data was available concerning the anticancer effects of its members
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