Abstract
SINCE SONG [13] AND BROMBERG [ 131 REINTRODUCED the use of porcine xenografts as a covering for burned patients there ha-s been considerable question whether the xenografts cause an immune reaction. Several observations [ 121 suggest that the xenograft does not cause an immune reaction: (a) The xenograft is not vascularized; (b) subcellular porcine skin extracts injected intradermally into human patients before and after porcine xenografting do not elicit delayed hypersensitivity; (c) and, this porcine skin extract, injected intravenously into rabbits, fails to produce precipitin antibodies against the extract. It is the purpose of this study to illustrate that by suitable assay procedures, the act of xenografting with porcine skin in burned patients elicits an immune reaction.
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