Anti-Obesity Effect of Carom Seeds (Trachyspermum Ammi) Tea on Bmi and Lipid Profile Leading to Cardiovascular Diseases

Abstract

Introduction: Obesity refers to the deposition of fat ratio in the fat tissues of muscles in which the BMI raised (obesity and hyperlipidemia) that may have a negative impact on health. Herbs from ancient times till today have been utilized as a solution for some infections and issues. Objectives: The purpose of this research was to evaluate the defensive impact of Carom seed (Trachyspermum ammi) against obesity and hyperlipidemia. Materials & Methods: Carom seed was acquired from the Faisalabad and was washed to expel the soil, dust, and outside materials clung to the test surface. The crude material was dried by utilizing an air forced draft oven. After planning, it was stuffed in water/airproof plastic containers and put away at 5 ± 1 °C until further analysis. Moreover, the blood samples were collected on 0-day, 15-day, 30-day, and 60-day by taking 15ml venous blood after a 12-hour night of fasting. Serum samples were separated by centrifugation and stored at -70?c until analysis. Low-density lipoprotein and high-density lipoprotein cholesterol were measured enzymatically. Concentrations of triglycerides and total cholesterol were measured by Peridochrom Triglyceride Kits. Sixteen subjects, separated into four groups were given carom seeds in the form of tea i.e. G0 (Control), G1 (500mg), G2 (1 mg) and G3 (1.5 mg) individually. This was an eight-week trial and all the parameters e.g. Body Mass Index, High-Density Lipid, Low-Density Lipid, Tri-Glycerides, and Total Cholesterol were measured at 0 days, 15 days, 30 days, and 60 days respectively. The yield data of carom seed tea for anti-obesity and anti-hyper-lipidemic effects obtained for each treatment were subjected to a paired t-test by using SPSS. Results: The significant change has been observed between the groups with the relevance of treatments given. G0 showed no significant changes among all the groups while G2 and G3 reported considerable changes because of the dosage concentrations of carom seed tea i.e. 1g and 1.5g respectively (p<0.05).