Abstract
Clonixin (Sch 10304) [2-(2’ methyl-3’ chloro anilino) nicotinic acid] has been reported to be an orally effective analgesic and a non-steroidal anti-inflammatory agent in rodents (1). Clonixin has no dependence liability in monkeys (2) and its analgesic effect is not antagonized by naloxone in mice and rats (3). Clinical results with clonixin have shown degrees of analgesic effects not usually observed with non-narcotic agents. Single oral doses of clonixin ranging from 300–600 mg produced pain relief comparable to that seen with parenteral administration of morphine (4).
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
