Abstract
Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis is the most common form of paraneoplastic encephalitis that is associated with teratomas. Because removal of the tumor leads to better clinical outcomes, determining the location of teratomas is essential. The authors report two cases of anti-NMDA receptor encephalitis with a small ovarian teratoma that could not be detected by usual imaging. Both cases had the diagnosis confirmed laparoscopically.
Highlights
Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis was identified in 2007 by Dalmau et al [1]. This encephalitis is a type of limbic encephalitis that is often found in young women with ovarian teratomas
Anti-NMDA receptor encephalitis often occurs with a small ovarian teratoma
In patients with anti-NMDA receptor encephalitis associated with ovarian teratoma, surgical resection of the tumor and subsequent immunotherapy are the most effective treatment strategies for improvement in symptoms
Summary
Anti-N-methyl-D-aspartate receptor encephalitis associated with a tiny ovarian teratoma diagnosed by exploratory laparoscopy: report of two cases. Summary Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis is the most common form of paraneoplastic encephalitis that is associated with teratomas. Because removal of the tumor leads to better clinical outcomes, determining the location of teratomas is essential. The authors report two cases of anti-NMDA receptor encephalitis with a small ovarian teratoma that could not be detected by usual imaging. Both cases had the diagnosis confirmed laparoscopically
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