Abstract
The existing antileishmanial drugs for complete cure of visceral leishmaniasis( Kala azar) are limited The available drugs are either toxic or less effective leading to disease relapse or conversion to postkala ?azar dermal leishmaniasis Several herbal extracts have been shown to have antileishmanial activity... In the present study, In vitro anti- leishmanial activitiy of Ethanolic ,Methanolic , Benzene, and Chloroform extracts of Chinopodiumambrosioides have been evaluated . Among those extracts ethanolic extract of Chinopodiumambrosioides shows effective antileishmanial activity against promastigote form of leishmanial donovani. ascoridole present in C.ambrosioides which may be responsible for inhibition the growth of parasites. It was found that IC 50 = 150 ?g /ml( 50% inhibition at 150 ?g /ml) and IC90 =200 ?g /ml (complete inhibition at 200?g /ml).. KEYWORDS :Visceral leishmaniasis, Chinopodium ambrosioides,Leishmaniadonovani,
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