Abstract
1-Citronellyl-5-phenylimidazole (KK-22) was applied topically and orally to and mixed in the diets of 4th instar silkworm larvae, and its anti-juvenile hormone (JH) activity was determined by the induction rates of precocious metamorphosis. Larvae were more sensitive at the earlier stages of 4th instar to KK-22 and there were no significant differences in induction of precocious pupation among the administration methods, topical application, oral ingestion and feedng on diet. Anti-JH activity of KK-22 vanished when methoprene, a JH analogue, was applied immediately after KK-22 treatment.
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