Abstract
The anti-inflammatory study (in vivo) was carried out on the different extracts (200g/kg) of Doum plant parts in comparison with Asprin (100g/kg). High activity was found in the chloroform and ethanol extracts of the seeds (27%, 22%), roots (24%, 20%), and leaves (25%, 20%), respectively. The chloroform extract of the seeds was the most active (27%). The anti-inflammatory study (in vitro) of the seed extracts was monitored using atropinized rat fundus strip by induced inflammations with kidney homogenate. The kidney homogenate (0.5ml) stimulate rat fundus strip contraction up to 20mm for 3min. Pre-incubation of the kidney homogenate in indomethacin (as standard, 5µg/ml) completely (100%) inhibited their stimulant effect. Whereas pre-incubation of the kidney homogenate in Doum chloroform extract of the seeds (5ng/ml) markedly inhibited the stimulate effect by 60%.
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