Abstract
Purpose The eyedrop form of rebamipide was approved in Japan for use in the treatment of dry eye diseases, because it up-regulates mucin secretion and production. Others reported that rebamipide, a gastroprotective drug, could not only increase gastric mucus production but also suppressed gastric mucosal inflammation and that it was dominantly distributed in mucosal tissues. In this study we investigated whether rebamipide has antiinflammatory effects in the ocular surface.
Highlights
The eyedrop form of rebamipide was approved in Japan for use in the treatment of dry eye diseases, because it up-regulates mucin secretion and production
We studied the effects of rebamipide on ocular surface inflammation in our murine experimental allergic conjunctivitis (EAC) model
We observed their condition of allergic conjunctivitis when we treated the dry eye patients accompanied with allergic conjunctivitis using rebamipide
Summary
From 9th Symposium of Experimental Rhinology and Immunology of the Nose (SERIN 2013) Leuven, Belgium. 21-23 March 2013. From 9th Symposium of Experimental Rhinology and Immunology of the Nose (SERIN 2013) Leuven, Belgium. Purpose The eyedrop form of rebamipide was approved in Japan for use in the treatment of dry eye diseases, because it up-regulates mucin secretion and production. A gastroprotective drug, could increase gastric mucus production and suppressed gastric mucosal inflammation and that it was dominantly distributed in mucosal tissues. In this study we investigated whether rebamipide has anti- inflammatory effects in the ocular surface
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
