Abstract
Abstract Objective In traditional folk medicine, Ceiba pentandra has been used for its anti-diabetic and anti-infective effects. This study investigates the anti-inflammatory and antioxidant activities of the aqueous extract of the plant’s leaves. Methods The anti-oedematous tests with carrageenan and lipoxygenase inhibition assay were carried out concerning anti-inflammatory studies. DPPH free radical scavenging, ferric-reducing antioxidant power, ABTS+ free radical scavenging assay, and lipid peroxide determination were investigated for antioxidant activities. Key findings As a result, C. pentandra extract inhibited edema between 3 and 5 h in the order of 83.07% and 94.09% at 200 kg. b.w. and lipoxygenase enzyme with a percentage of 87.11 ± 3.02%. This study used the lipid peroxidation level as a marker. The results of the lipid peroxidation test show a percentage inhibition of 49.60%, close to Trolox 48.11%, and present a good antioxidant activity compare with the free radical scavenging assay. Conclusions The aqueous decoction of C. pentandra leaves has demonstrated anti-inflammatory solid activities as well as lipid peroxidation due to the presence of phytochemical groups of interest such as sterols, polyphenols, quinones, catechin tannins, flavonoids, and saponins.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have