Abstract

The ethanolic leaf extract of Setaria megaphylla (100-300 mg/kg) wasinvestigated for pharmacological properties against egg white albumin - induced inflammation, Chemical as well as thermal- induced pain. The extractdemonstrated a dose – dependent anti- inflammatory and antinociceptiveactivities. These activities were comparable to that of ASA (100mg/kg). The leaf extract possess anti inflammatory and analgesic properties, which can beexploited in health care (Afr. J. Biomed. Res. 9: 229 – 233)Keywords: Setaria megaphylla, anti inflammatory, analgesic.

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