Abstract
The anti-inflammatory activity of a number of triterpenoids and a nor-triterpenoid isolated from Indian plants has been tested against carrageenin-induced oedema and formaldehyde-induced arthritis in albino rats. The triterpenoids of the oleanene and ursene series and filicene were found to be active in both the tests. The nor-triterpenoid, nimbin was also active. The other triterpenoids such as lupeol acetate, ursolic acid, taraxerol and cucurbitacin were devoid of anti-inflammatory activity. The structure-activity relationship of these triterpenoids is discussed.
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