Abstract

Whitehouse MW, Fairlie DP. Anti-inflammatory activity of a holothurian (sea cucumber) food supplement in rats. Inflammopharmacology. 1994;2:411-417. A human food supplement (SeaCare ) composed of dried extracts from specific varieties of holothurians (sea cucumbers) and a sea plant has been found to have anti-inflammatory activity in both sexes of two strains of rats. It is slightly less active than aspirin (w/w) against the acute carrageenan-induced paw inflammation, but without the gastrotoxicity of aspirin. It is also active against adjuvant-induced polyarthritis in rats on a daily dose schedule.

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