Abstract
Inflammation is one of the means the human body uses to defend itself in the event of infection, trauma, or exposure to toxic substances and it is closely associated with a number of disease sympto...
Highlights
It is widely known that inflammation is associated with most diseased conditions
To evaluate the anti-inflammatory activities of the extracts, acute inflammation was induced in chicks using carrageenan
Subcutaneous administration of carrageenan resulted in a noticeable increase in paw size of the chicks
Summary
It is widely known that inflammation is associated with most diseased conditions. Inflammation is usually characterized by redness, heat, pain, swellings, and disruption in normal physiological functions. The body uses inflammation as a protective response to infection, injury (or trauma), or chemical exposure. Colitis, hepatitis, and arthritis, which are all inflammatory diseases, have been implicated as a leading cause of permanent disability and death in people worldwide (Emery, 2006). Steroidal and non-steroidal anti-inflammatory agents are used to manage inflammation cases. Reported side effects associated with the use of these drugs have, been unpleasant. The long term use of steroidal and non-steroidal anti-inflammatory drugs is understood to lead to drug-induced toxic effects and/ or secondary adverse effects (Beg, Hasan, Hussain, Swain, & Barkat, 2011; Drew & Myers, 1997). The search for new anti-inflammatory agents with improved efficacy and limited side effects has become the focus of global scientific research, with natural products leading the way
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