Abstract

Inhibitory effects of the mushrooms on the growth and urease ofHelicobacter pylori (HP), which is associated with human gastroduodenal diseases such as gastritis, peptic ulcer and gastric carcinoma, were investigated. Most of the mushroom extracts did not show inhibitory effect on HP urease exceptCoriolus versicolar, Auricularia auricula, Sarcodon aspratus andFlammulina velutipes. The extract ofGanoderma lucidum, Coriolus versicolar, Gyropora esculenta andAgaricus bisporus var. albidus inhibited the growth of HP. When their extracts were fractionated, the ether fraction ofGanoderma lucidum andAgaricus bisporus var. albidus were the most effective. Among seven components seperated from the ether fraction ofG. lucidum extract by silica gel column chromatography, P3 was the most potent: MIC was 200 μg/ml. However, P3 did not inhibit the urease.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.