Abstract
<strong>Background:</strong> The clinical spectrum of anti-glutamic acid decarboxylase (GAD) antibody-associated neurologic syndromes is expanding, with focal, generalized, and atypical forms. <strong>Case Report:</strong> We describe a 59-year-old female showing continuous right lower limb myoclonus and mild encephalopathy. These symptoms started 2 weeks prior to evaluation. The patient had great improvement with intravenous steroids. An autoantibody panel was positive for anti-GAD. <strong>Discussion:</strong> Various clinical manifestations, including myoclonus, may relate to anti-GAD antibodies. The treatment options available include symptomatic drugs, intravenous immunoglobulin, steroids, and other immunosuppressant agents.
Highlights
Case ReportsPedro Manzke1,2*, Talyta Grippe[1,2], Georgia L
We present a 59-year-old female with continuous involuntary movements of her right leg
A similar case has previously been reported, but myoclonus was seen on both legs and there was no associated encephalopathic features.[2]
Summary
Pedro Manzke1,2*, Talyta Grippe[1,2], Georgia L. Leal[1], Emmanuel Roze[3,4], Emmanuelle Apartis[3,5], Ronaldo Maciel Dias1 & Andre G.
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