Abstract
Fresh leaves of Pseuderanthemum palatiferum Radlk. were claimed to cure various disease including diabetes mellitus in Thai people. However, hypoglycemic and anti-diabetic activities of P. palatiferum have not been reported. This study examined the hypoglycemic and anti-diabetic effects of P. palatiferum leaf aqueous extracts by an oral glucose tolerance test (OGTT) in normal and streptozotocin-induced diabetic rats [1]. A single oral administration of the aqueous extract at doses of 0.25 and 0.50g/kg significantly decreased the blood glucose level in STZ-induced diabetic rats but not in normal rats. A reference drug, glibenclamide, at a dose of 5mg/kg showed a significant blood glucose lowering effect both, in normal rats and STZ-induced diabetic rats. Phytochemical screenings to examine compounds responsible for the biological activity were carried out by color and precipitation tests [2]. It was found that the extract contained flavonoids, phenolic compounds, non-volatile lactones and saponins.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
