ANTI-CANDIDAL EFFICACY OF OREGANO IN DENTAL PROSTHETICS

Abstract

Introduction: Denture hygiene is considered as an essential part of oral hygiene maintenance for the well-being of oral soft tissue in denture wearers. Denture induced stomatitis is common among denture wearers and that can be due to adherence of candida species.The purpose of the present study is to determine and compare the anti-candidal effect of Oregano against Candida albicans for using it efciently as a denture cleansing agent. Swab from the tissue surface of 20 complete acrylic denture wearers w Materials And Methods: ere collected and cultured to isolate the Candida albicans. The plant materials were soaked in 99.9 % ethanol and pure extracts were made by the cold maceration method. Various concentrations of Oregano (1 %, 2 %, 4 %, 8 % and 16 %) dilutions were done. Fluconazole was taken as a control to compare with the plant products. The Disc diffusion method was done to nd the zone of inhibition by pre-treating the discs with herbal extracts. The zone of inhibition was measured in millimetres. The mean value of zone of inhibition of Oregano w Results: as less when compared to the uconazole of higher concentrations. The differences between two groups were analyzed using one way ANOVA test. Oregano showed least anti-candidal Conclusion: effect when compared to uconazole, Where it can have effects on other species of candida