Anti-bacterium influenced corrosion effect of antibacterial Ti-3Cu alloy in Staphylococcus aureus suspension for biomedical application

Abstract

Titanium and titanium alloys have been widely used as dental and orthopedic materials. The infection and the bacterium influenced corrosion both are concerned problems. Ti-3Cu alloy exhibits strong antibacterial properties against E. coli and S. aureus. The strong antibacterial properties of Ti-3Cu provides with a potential new method to reduce the bacterium influenced corrosion. S. aureus suspension was selected to simulate a serious bacterial condition. The corrosion behavior of Ti-3Cu alloy in S. aureus suspension was investigated by an electrochemical testing and an immersion test in comparison with pure titanium. Electrochemical results showed that Ti-3Cu exhibited a much better anti-corrosion property than cp-Ti in S. aureus suspension. Surface observation demonstrated that no corrosion pit was observed on Ti-3Cu alloy after 30 days immersion in the suspension while lots of corrosion pits were found on cp-Ti. The biofilm formation on the surface was observed by scanning electronic microscopy (SEM) in different periods. It has been revealed that S. aureus could grow and gather on the surface of cp-Ti to form biofilm after 18 h immersion, but only several bacteria were found on Ti-3Cu alloy even after 24 h immersion, displaying that Ti-3Cu alloy exhibits very strong anti-adhesion properties against S. aureus. It was concluded that Ti-3Cu performs a super anti-corrosion property due to the strong anti-adhesion property, in which Ti2Cu precipitate plays a critical role.