Anti-bacterial potential of (Acacia nilotica, Trigonella foenum-graecum, Punica granatum and Commiphora myrrha) crude extracts against diverse drug sensitive and resistant bacterial species

Abstract

The alarming increase in bacterial resistance to antibiotics caused some authors to state that we are approaching a post-antibiotic era and medical catastrophe, the study aimed to assess the antimicrobial effects of selected plant extracts against several sensitive and resistant bacterial isolates. Experimental cross-sectional study was conducted, 70% ethanol crude Acaccia nilotica, Trigonella foenum-graecum, Punica granatum and Commiphora myrrha extract was prepared and several commercial antimicrobials agent tested, the antibacterial activity was investigated using the disc diffusion method. The inhibition zones' diameters (mm) were calculated and interpreted by Zone Diameter Interpretative Standards. Data were analyzed by using (SPSS) software version 22. About 200% of A. nilotica and T. foenum-graecum showed bactericidal effects against Enterococcus faecalis, means ±SD (12.3 ± 2.8 and 12.5 ± 2.1). The activity of 200% C. myrrha extract was highest against all diverse bacterial. Despite a relatively high inhibition zone among all plant ethanol extracts, the findings demonstrate that there is no statistical significance in the inhibitory activity impact of varying concentrations of 70% ethanol extracts of all plants extract against bacterial isolates (P. value ? 0.05). The outcomes of the ethanol extracts of the used plant under study demonstrated that the herbal extract can be a superior antimicrobial potential than the result of the commercial broad spectrum antimicrobial agent utilized. C. myrrha extract was potent antimicrobial activity against all diverse bacterial species.