Anti-aging technologies and physiotherapy innovations

Abstract

Abstract. At present, aesthetic anti-aging programs have acquired a new semantic content, since, on the one hand, they demonstrate the modern level of development of medicine and, on the other hand, the unity of external aestheticism with the somatogenic status of patients, both men and women. The purpose of the study was to improve the quality of anti-aging medical and aesthetic care for patients with varying degrees of age-related structural changes in the skin of the face and body, by including a combined anti-aging program with the use of injectable carboxytherapy, platelet-rich plasma (PRP), exercise therapy, a dietary program, and nutritional support (trace elements of zinc, copper, selenium, vitamins B and D) in the treatment protocol. Patients and methods: 114 patients (56 men and 58 women) with involutive face / body skin changes were studied. Prior to the combined anti-aging program, all patients underwent an anthropometric assessment (body mass index — BMI), dermatological control (dermatoscopy, ballistometry, corneometry, cutometry), and an assessment of antioxidant functions according to liquid chromatography and mass spectroscopy (superoxide dismutase — SOD, total antioxidant function index). Simple open-label randomization made it possible to divide men and women into homogeneous comparable groups: group I (n = 30) received injectable carboxytherapy along the cosmetic lines of the face and in the décolleté; group II (n = 30) received platelet-rich plasma in the form of platelet therapy in the specified areas; group III (the study group, n = 32) were treated with a combined technique including simultaneous PRP and injectable carboxytherapy; group IV (the control group, n = 22) had basic facial and body care, without physiotherapy methods. The statistical data analysis was carried out in Microsoft Office Excel (2017) and SPSS statistical processing (PASW Statistics version, 2018). Parametric (the linear correlation method, the Students test) and non-parametric methods (the Spearman»s rank correlation coefficient, the Wilcoxon and Mann-Whitney Test) were used. The differences were considered significant at p < 0.05. Results: after the combined therapy, there was a significant increase in the hydration index of the facial skin by 13.2 ± 1.2 standard units, an increase in the level of elastin by 9.4 ± 2.9 standard units, a decrease in the depth of wrinkles by 1.4 points, correction of superoxide dismutase values from 135 [133; 137] ng / mL to the physiological norm of 112.4 [111.9; 112.9] ng /mL (p < 0.01), and an improvement in the overall antioxidant function of the blood.