Abstract
Anti-aging is one of the top goals in the field of health care and aesthetics. Anti-aging cosmetics derived from nature are oriented to long-term development, bringing safety to users and being environmentally friendly. The aim of this study was to develop an anti-aging cosmetic formulation process based on coconut oil in combination with deer antler stem cell extract. The results show that the presence of deer antler stem cell extract added to the foundation made the serum product highly stable and helped improve skin aging significantly after 2 weeks of use. The skin site where the serum product was applied showed a smooth and elastic skin surface, with very few fine lines and shallow wrinkles. Serum reduced the number of wrinkles (48.09% compared to commercial serum (ME) and 60.31% compared to positive control (PC)), reduced skin recovery time (39.31% compared to ME and 67.1% of PC) after two weeks of use. After 2 weeks of use, collagen density increased 10.18% compared to ME and 63.76% compared to control. Epidermal thickness increased by 106.1% compared to PC and 121.7% compared to ME.
Highlights
The skin is the largest organ of the human body and serves as a protective barrier against biological, chemical and physical stress
Prepare Serum from Coconut Oil Base Bombined with Deer Antler Stem Cell Extract After the survey found that the formula with HLB = 5.5 for the most stability and sustainability, the HLB value of coconut oil was 5.5
Serum reduces the number of wrinkles (48.09% compared to commercial serum (ME) and 60.31% compared to control (PC)), reduces skin recovery time (39.31% compared to ME and 67.1% compared to PC) after two weeks of use
Summary
The skin is the largest organ of the human body and serves as a protective barrier against biological, chemical and physical stress. The main external signs of skin aging include the appearance and increase of wrinkles and loss of skin density [2,3]. When the aging process takes place, the epidermis shows signs of rapid keratinization, slow cell regeneration, increased sensitivity to UV rays, making the internal structure of the skin weak and susceptible to damage, infections and slow wound healing [2]. Along with the lack of elastin and the loss of a large amount of natural collagen, the dermis tissue is destroyed, the skin structure becomes weaker. This is considered the main cause of wrinkles on the skin, reduced skin density and reduced elasticity of the skin [2]
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