Abstract

BackgroundThe major types of hormonal contraception used currently in Ethiopia are progestogen-only. This study aimed to assess the differences in anthropometry indices, blood pressure, and lipid profile among women using progestin-only contraceptives in selected health facilities of Jimma town, southwest Ethiopia.MethodsA facility-based comparative cross-sectional study was conducted among women of reproductive age using Depo-medroxyprogesterone acetate (DMPA) and implant in selected health facilities from April 11 to May 11, 2019. A total of 146 women (45 DMPA and 51 implant users and 50 non-users) were selected randomly for inclusion in the study. One-way analysis of variance was used to examine variations in health outcomes while Bonferroni post-hoc tests were conducted to determine significance of variations between multiple outcomes.ResultsThere was a statistically significant difference in the mean Body Mass Index (p = 0.045), Hip-to-waist ratio (p = 0.012), systolic blood pressure (p = 0.027), diastolic blood pressure (DBP) (p = 0.017), total cholesterol (TC) (p = 0.005), low-density lipoprotein (p = 0.023) and triacylglycerol (TAG) (p = 0.000) between women using progestin-only contraceptives and non-users. DMPA users had higher TC (p = 0.024) than non-users. Results from Pearson correlation analysis showed that DBP of DMPA users was higher with longer duration of use.ConclusionThe findings suggest the need for family planning service providers to undertake appropriate client profiling before recommending a particular method to women seeking the services in order to minimize adverse health risks, especially for those who may have pre-existing conditions.

Highlights

  • IntroductionThis study aimed to assess the differences in anthropometry indices, blood pressure, and lipid profile among women using progestin-only contraceptives in selected health facilities of Jimma town, southwest Ethiopia

  • The major types of hormonal contraception used currently in Ethiopia are progestogen-only

  • Exclusion criteria Women of reproductive age using the methods who had a history of chronic illness including diabetes, hypertension, liver dysfunction, cardiovascular disorders (CVD) and lipid profile and blood pressure (BP) affecting drug and breastfeeding mothers were excluded by reviewing their medical records and/or by asking

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Summary

Introduction

This study aimed to assess the differences in anthropometry indices, blood pressure, and lipid profile among women using progestin-only contraceptives in selected health facilities of Jimma town, southwest Ethiopia. The major types of hormonal contraception used currently in Ethiopia are progestogen-only. They are available in the form of progestogen-only pills, subdermal implants, injection and hormones-releasing intrauterine systems [1]. Nausea, breakthrough bleeding, breast tenderness, increased blood pressure and high level of cholesterol are commonly reported progestin-only contraceptive side effects [4]. Progestin-only contraceptives have been shown to alter the lipid profile, body weight, and blood pressure among various population groups with different patterns of dyslipidemia and cardiovascular (CV) disease risks [5]

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