ANTHROPOMETRIC AND BIO-IMPEDANSOMETRIC PARAMETERS AS DIAGNOSTIC PREDICTORS IN PATIENTS WITH GASTRIC CANCER

Abstract

The study of anthropometric and bioimpedance parameters in assessing the physical development of patients helps to clarify the diagnosis, predict the course of the disease, and identify groups of increased risk for the development of the disease. The aim of this study was to identify anthropometric and bioimpedance metrics in patients with stomach cancer. Anthropometric and bioimpedansometric examination of 250 patients with verified gastric cancer, 123 men and 127 women was carried out. As a comparison group, the study used the results of anthropometric and bioimpedance measurements of healthy 221 men and 267 women of the same age in the Krasnoyarsk Territory population. To determine a set of anthropometric and bioimpedansometric variables, allowing to classify the observed people depending on the presence (group of patients with gastric cancer) or the absence of stomach cancer (group of healthy people), the method of discriminant analysis was applied. To test the hypothesis about the homogeneity of the covariance matrices of the compared groups, the multidimensional Box M-criterion was used. The statistical significance of the power of the discriminant function was assessed using the Wilks test. For each discriminant function, the role of its components was assessed by comparing the matrices of total variances and covariances using the F-test. Shoulder diameter for men and women, chest diameter (transverse size) for men and women, waist circumference for men, waist / hip ratio for men and women; lean mass in men, total fluid in men, fat mass in women, phase angle in men and women are statistically significantly different in the observed groups. The developed discriminant models with an accuracy of 75-77% suggest the presence of gastric cancer in patients and can be used in clinical practice at the stage of general medical examination in groups at increased risk of developing the disease.