Abstract

Anthropogenic impact on the development of resistance to antibio­tics in microorganisms of the Uzh River (Ukraine)

Highlights

  • The issue of antibiotic resistance of microorganisms arose in the 1950s after the first antibiotics that radically changed approaches to the treatment of infectious diseases had been discovered

  • The obtained results that establish a correlation between the concen­ trations of chemical substances in water and the activation of antibiotic resistance in microorganisms can indicate the degree of aquatic ecosystems transformation under anthropogenic impact

  • The aim of this work was to determine the correlation between the content of heavy metals (Cu, Ni, Zn, Cr) and nitrogen compounds (NO3, NO2 and NH4) and the amount of antibiotic resistant microorganisms in research sites on the Uzh River (Ukraine) affected by anthropogenic impact of different character

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Summary

Introduction

The issue of antibiotic resistance of microorganisms arose in the 1950s after the first antibiotics that radically changed approaches to the treatment of infectious diseases had been discovered. Based on our seasonal moni­toring during 2016–2017, which included determining the content of nitrogen compounds and heavy metals in the research sites, and as a result of the study on the microbiocenosis structure with a subsequent determination of antibiotic sensitivity of the dominant strains isolated from water samples, we conducted analysis of the correlation between the concentrations of these substances and the distribution of antibiotic resistant strains. This enabled us to identify the potential factors that contribute to the deve­lopment of antibiotic resistance in microorganisms

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