Anthelmintic resistance to cattle gastrointestinal nematodes in selected dairy farms of Mymensingh and Sirajganj districts of Bangladesh

Anita Rani Dey,Md Hasanuzzaman Talukder,Md Shahadat Hossain,Mohammad Zahangir Alam,Saiful Islam,Tm Mahibur Rahman

doi:10.3329/ralf.v5i1.36556

Anita Rani Dey, Md Hasanuzzaman Talukder + Show 4 more

Open Access

https://doi.org/10.3329/ralf.v5i1.36556

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Abstract

Correction: Table 1 and Table 2 have were omitted from the PDF in error. They were added to page 89 on 17th May 2018.Anthelmintic resistance (AR) to commonly used dewormers is one of the major world-wide constrain in livestock production. The present study was investigated the status of AR in BAU dairy farm, Mymensingh and Talukder dairy farm, Sirajganj. Faecal egg count reduction test (FECRT) was applied to assess AR in cattle of two dairy farms during January to June 2017. The anthelmintics tested were Albendazole (ABZ), a benzimidazole anthelmintic (Almex®, Square Ltd.) and Ivermectin (IVM) (Vermic®, Techno drugs Ltd.), administered at the doses recommended by the manufacturers. In each farm, cattle were divided into treatment and control (not treated) group based on faecal egg counts (FEC), that is at least 200 eggs/g. At 14 days after treatment, faecal samples were collected for post-treatment FEC, which is compared between treatment and control group. Resistance was defined if there was <95% reduction, with lower 95% confidence limit (CL) <90% in the FEC. AR was present in both the dairy farms involved in this study. The FECRT using ABZ revealed 79.7% (95% CL 87.9, 65.8) reduction and 95.8% (95% CL 98.7, 87.1) reduction of FEC in BAU and Talukder dairy farms, respectively. Also, FECRT using IVM revealed 77.9% (95% CL 97.7, 85.5) and 94.2% (95% CL 97.7, 85.5) reduction of FEC in BAU and Talukder dairy farms, respectively. Our study suggest that AR is present in both selected dairy farms and further extensive studies are required to determine the extent of AR in different cattle farms of Bangladesh.Res. Agric., Livest. Fish.5(1): 87-92, April 2018

Highlights

Anthelmintic resistance (AR) in gastrointestinal (GI) helminth population is widely recognized emerging problem in many parts of the world
On day 0, Cattle with faecal egg counts (FEC) >200 eggs per gram (EPG) of feces were randomly distributed into 3 treatment (1-3) groups and 1 control group
Faecal egg count reduction test (FECRT) ABZ The faecal egg count reduction (FECR) % for ABZ revealed 79.7% (95% confidence limit (CL) 87.9, 65.8) reduction and 95.8% (95% CL 98.7, 87.1)

Summary

Introduction

Anthelmintic resistance (AR) in gastrointestinal (GI) helminth population is widely recognized emerging problem in many parts of the world. Anthelmintics offer a simple, cheap, cost-effective method of controlling nematodes. They kill existing parasites and reduce the production of eggs. They can prevent disease in infected animals and reduce the intensity of future infection in infected animals and their offspring. There are three major classes of drugs used to control nematodes in livestock: benzimidazoles (ABZ), nicotinic agonists (levamisole) and macrocyclic lactones (IVM). Resistance is evolving in nematode populations to all three classes of anthelmintic (Bartley et al 2004)

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