Anthelmintic activity of (Mugwort) extracted with ethanol and rice gruel solvents

Abstract

This laboratory study was carried out to explore the anthelmintic properties of (Mugwort) extracts aligned with Indian earthworms Alcoholic extract and Rice Gruel extract of leaves were used as test. Albendazole was incorporated as standard drug and normal saline as control. Observations were made for the time taken to paralyze and death of the earthworm. Three concentrations 30, 60, 100mg/ml of every extract and standard drug at the concentration of 30mg/ml were studied. The outcome of study indicated that rice gruel extract of exhibited anthelmintic activity significantly higher than standard and also in a dose dependent manner. For the ethanolic extract group the time of paralysis and death time was 3.38 minute and 13.82 minute, while rice gruel extract group showed shortest time of paralysis (P) at 2.12 minute and death (D) at 7.45 minute of earthworms at higher concentration 100mg/ml as compared to standard Albendazole (30mg/ml) paralysis 2.27 minute and death at 6.44 minute respectively. Rice gruel extract showed more pronounced effect than ethanolic extract. Whereas the control group worms were observed for full day and night and there was no paralysis or death was found during that period.