Abstract
Abstract Purpose To evaluate cross‐sectional conjunctivochalasis area (CChA) and tear meniscus area (TMA) using Fourier‐Domain‐RTVue‐100 optical coherence tomography (OCT) before and after conjunctival cauterization and to evaluate inter‐ and intraobserver reliability. Methods A total of twelve eyes of 7 patients with conjunctivochalasis aged 56 to 87 were evaluated. After topical anesthesia, conjunctival cauterization was performed on the inferior bulbar conjunctiva. All patients underwent anterior segment OCT (AS‐OCT) imaging prior to and 4 weeks after the procedure. Cross‐sectional TMA and CChA at 3 locations (nasal, center and temporal areas) were measured in all patients. Results Non‐significant increases (p= 0.177) in TMA as a whole (3 locations combined) were observed at following cauterization. CChA measurements significantly decreased in all 3 locations after cauterization (p< 0.001). Mean CChA decreased from 0.247 ± 0.24 mm2 to 0.054 ± 0.79 mm2. For two measurements of TMA by examiner 1, intraclass correlation coefficients (ICC) ranged from 0.998 to 0.999. Among two examiners, Cronbach’s alpha reliability coefficients were as high as 0.993 and 0.997 before and after conjunctival cauterization. Regarding the CChA measurements, ICC values were similar to those of TMA, but Cronbach’s alpha reliability coefficients were slightly less. Conclusion This study indicates the AS‐OCT is a useful and reproducible instrument to measure cross‐sectional area of conjunctiva prolapsing into the tear meniscus of patients with conjunctivochalasis. The method can monitor effectiveness of thermo reduction of conjunctivochalasis.
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