Abstract
Anterior segment optical coherence tomography (ASOCT) is an imaging modality that provides both quantitative and qualitative information on the cornea, anterior chamber angle, iris and crystalline lens. ASOCT shows excellent repeatability and reproducibility for the measurement of corneal thickness, anterior chamber angle and anterior chamber depth. With realtime video recording, ASOCT can also effectively capture the dynamic changes of the iris and lens in response to light and eye accommodation. With this additional information, physiological and pathological changes of the anterior segment structures are now better understood. This article aims to provide an overview of the current applications of ASOCT in glaucoma.How to cite this articleLi H, Jhanji V, Dorairaj S, Liu A, Lam DSC, Leung CK. Anterior Segment Optical Coherence Tomography and its Clinical Applications in Glaucoma. J Current Glau Prac 2012;6(2):68-74.
Highlights
Assessment of the anterior segment is an integral part of ophthalmic examination
Ophthalmic optical coherence tomography (OCT) was initially developed for retinal imaging and used a near-infrared 800 nm superluminescent diode (SLD) as the light emitting source
Quantitative assessment of the anterior chamber angle (ACA) was first described by Pavlin and Foster in ultrsound biomicroscopy (UBM)
Summary
Assessment of the anterior segment is an integral part of ophthalmic examination. Traditionally, the anterior segment and iridocorneal angle are evaluated with the help of a slit lamp and gonioscope. Two anterior segment OCT (AS-OCT) models are commercially available-the Visante OCT (Carl Zeiss Meditec, Dublin CA, USA) and the slit-lamp OCT (SLOCT) (Heidelberg Engineering, GmbH, Dossenheim, Germany). Ophthalmic OCT was initially developed for retinal imaging and used a near-infrared 800 nm superluminescent diode (SLD) as the light emitting source This OCT model was subsequently applied to anterior segment imaging, capturing images of the cornea, anterior chamber angle, iris and crystalline lens.[2,3,4,5,6,7] this type of OCT was limited by its light source and imaging speed (400 A-scans per second). Two AS-OCT models are commercially available (Table 1)—the ZEISS VisanteTM OCT Model 1000 (Visante OCT) (Carl Zeiss Meditec, Dublin CA, USA) and the SlitLamp OCT (SLOCT) (Heidelberg Engineering, GmbH, Dossenheim, Germany) Both equipped with a 1310 nm SLD, they provide rapid, noninvasive imaging of the anterior segment with the patient in upright position. After manual location of the scleral spur, the interscleral spur distance, angle opening distance (AOD 500, AOD 750), trabecular-iris spur area (TISA 500, TISA 750), trabecular-iris angle (TIA 750) and the scleral spur-to-scleral spur distance are measured semiautomatically
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